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The conceptofsuper-equivalentexchangeincludesthe exchange of ions, absorption of electrolyte molecules without ion exchange, and other processes which could be characterized as between the above two cases. : MRP II Precision Tool Co. Hyman Zimmerman, in an observation known as Hys rule, noted that if both drug- induced hepatocellular injury and jaundice were present simultaneously without biliary obstruction (or hemolysis), a mortality rate of at least 10 could be expected.

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